Effects of exercise and sporting activity in gynecological cancer patients on quality of life, body composition and prognostic biomarkers

Effects of exercise and sporting activity in gynecological cancer patients on quality of life, body composition and prognostic biomarkers - Begyn

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00024829

Enrollment

110

Registered

2021-03-24

Start date

2019-10-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C50 C56

Interventions

Group 1: Patients will be studied during routine follow up presentations every three months up to 12 months after initial diagnosis.

Eligibility

Sex/Gender

Female

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: • Women> 18 years • Gynecological cancer • Treatment at the Homburg University Women's Clinic • Sufficient language skills to fill out the questionnaires

Exclusion criteria

Exclusion criteria: • pregnancy • Immobility (e.g. unstable spine with osseous metastasis) - only as a control group without physical activity.

Design outcomes

Primary

Measure	Time frame
Influence of physical activity / movement on • General physical health o Fitness test (5-minute walk test ...) o body weight o blood pressure o Glucose metabolism • The body composition (body fat percentage, muscle mass, etc.) o Bioelectrical impedance analysis o Calipometry • Biomarkers relevant to prognosis o White blood cell counts, tumor markers, liver and kidney values o Lymphocyte subpopulations o Interleukin profiles in serum • the quality of life and the psychosocial outcome o Quality of life: EORTC-QoQ C30 (Aaronsen 1993) o Distress Thermometer (Mehnert 2006) o mental illness (depression, anxiety disorder, fatigue) o Professional reintegration Influence of different forms and intensities of physical activity / movement on therapy adherence / feasibility of oncological therapy (endocrine therapy, chemotherapy (postponement / dose reduction of protocols due to pathological laboratory values) o Metabolic efficiency of task (MET) o With group connection (running training, Nordic walking group, RehaSport) o Without group connections (swimming, running, fitness studio)	—

Measure

Time frame

Influence of physical activity / movement on • General physical health o Fitness test (5-minute walk test ...) o body weight o blood pressure o Glucose metabolism • The body composition (body fat percentage, muscle mass, etc.) o Bioelectrical impedance analysis o Calipometry • Biomarkers relevant to prognosis o White blood cell counts, tumor markers, liver and kidney values o Lymphocyte subpopulations o Interleukin profiles in serum • the quality of life and the psychosocial outcome o Quality of life: EORTC-QoQ C30 (Aaronsen 1993) o Distress Thermometer (Mehnert 2006) o mental illness (depression, anxiety disorder, fatigue) o Professional reintegration Influence of different forms and intensities of physical activity / movement on therapy adherence / feasibility of oncological therapy (endocrine therapy, chemotherapy (postponement / dose reduction of protocols due to pathological laboratory values) o Metabolic efficiency of task (MET) o With group connection (running training, Nordic walking group, RehaSport) o Without group connections (swimming, running, fitness studio)

—

Secondary

Measure	Time frame
o Influence of biomarkers on progression-free survival and mortality	—

Countries

Germany

Contacts

Public ContactCosima Zemlin

Universitätsklinikum des Saarlandes, Klinik für Gynäkologie, Geburtshilfe und Reproduktionsmedizin

cosima.zemlin@uks.eu+491729681417

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 14, 2026