Post-operative Cognitive dysfunction
Conditions
Interventions
Group 1: Group P - Inj Fentanyl only given as pre-medication for sedation
Group 2: Group K - Inj Fentanyl and Inj Ketamine (0.5mg/kg) given as pre-medication for sedation
Sponsors
Army Hospital (R&R), Delhi University
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. All women undergoing oocyte retrieval at ART cetner, Army Hospital( R &R) 2. ASA 1 and 2 3. Ability to read and understand either Hindi or English
Exclusion criteria
Exclusion criteria: 1. Patient refusal 2. BMI>30 kg/m² 3. Pre-existing psychiatric conditions 4. Pre-existing respiratory conditions 5. Pre-existing cardiovascular disease 6. Procedures lasting more than 30 min or less than 10 mjn 7. Procedures converted to GA requiring muscle relaxants 8. Known allergy to soy protein, egg protein, or ajy of the drug involved.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measuring the recovery of cognitive function using MMSE at 60 min and 4 hours after cessation of procedural sedation. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Compare hemodynamical and respiratory states in the 2 groups 2. Comparing time to spontaneous eye openjng after cessation of sedation. 3. Comparison of rescue dose of profofol used 4. Comparison of operating conditions | — |
Countries
India
Contacts
Public ContactMudit Varshney
Army Hospital (R&R)
Outcome results
None listed