[18F]PI-2620 tau PET in frontotemporal dementia

[18F]PI-2620 tau PET in frontotemporal dementia - FTAUD

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00024770

Enrollment

100

Registered

2023-04-06

Start date

2023-01-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G31.0

Interventions

Group 1: Patients with the clinical diagnosis of FTD. They will undergo dynamic (0-60min p.i.) PI-2620 PET/MR imaging. The PET data will be subjected to kinetic modelling which will result in parametr

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: FTD or healthy No pregrancy No breast feeding No other neuropsychiatric diseases No 3T MRI contraindications No claustrophobia

Exclusion criteria

Exclusion criteria: Pregnancy Breast feeding Other neuropsychiatric diseases 3T MRI contraindications Claustrophobia

Design outcomes

Primary

Measure	Time frame
Sensitivity and specificity of PI-2620 PET to diagnose FTD, as obtained by a four-field table once the final study cohort size is achieved	—

Secondary

Measure	Time frame
Sensitivity and specificity of PI-2620 PET to diagnose the different FTD subtypes	—

Countries

Germany

Contacts

Public ContactHenryk Barthel

Universitätsklinikum Leipzig

henryk.barthel@medizin.uni-leipzig.de+49 341 9718082

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026