U07.1
Conditions
Interventions
Group 1: Individuals with a SARS-CoV-2 infection who have been vaccinated for COVID-19
Group 2: Individuals with a SARS-CoV-2 infection who have not been vaccinated for COVID-19
Sponsors
Universitätsklinikum Erlangen, Virologisches Institut - Klinische und Molekulare Virologie
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: • Informed consent; in the event of inability to give consent, submission of the declaration by a representative in the case of presumably positive will of the proband • Sufficient knowledge of German to understand the subject information and answer the questionnaires • SARS-CoV-2 infection detected by at least one positive SARS-CoV-2 RNA detection using PCR in a respiratory sample. The first positive SARS result must not be more than two weeks ago. • Vaccinated against COVID-19 at least once (for the subcohort of vaccinated individuals) • Existence of a declaration of consent
Exclusion criteria
Exclusion criteria: • Inability to give consent due to diseases that are not relevant to the study • Inability to give consent and conflicting expressed or presumed will • COVID-19 vaccination carried out (for the subcohort of not vaccinated individuals)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| a) Characterization of differences in the clinical, immunological and virological course of the SARS-CoV-2 infection b) Analysis of the causes of breakthrough infections c) Identification of individual, immunological and genetic risk factors for inadequate COVID-19 vaccination protection or a more severe course of the disease d) Surveillance of SARS-CoV-2 variants that lead to a vaccine escape or immune scape | — |
Countries
Germany
Contacts
Public ContactPhilipp Steininger
Universitätsklinikum Erlangen, Virologisches Institut - Klinische und Molekulare Virologie
Outcome results
None listed