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Risk factors and therapy strategies of a first line treatment failure after invasive fungal infections

Risk factors and therapy strategies of a first line treatment failure after invasive fungal infections

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00024735
Enrollment
200
Registered
2021-04-09
Start date
2018-05-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

invasive fungal diseases

Interventions

Group 1: One-armed observational study. Only laboratory, clinical and imaging parameters from routine clinical practice are collected retrospectively. There are no interventions.

Sponsors

Universitätsklinikum Heidelberg
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Since this is a purely retrospective data analysis, there is no recruitment of patients; rather, patient records are screened to identify suitable records for analysis. The data sets are drawn from the files of patients who suffered from invasive candidiasis [candidemia, intra-abdominal candidiasis (IAC)], invasive aspergillosis (IA), invasive pulmonary aspergillosis (IPA) or any other invasive infection between January 2006 and December 2016 with rare fungal species suffered. In addition, patients should be included who only have a positive galactomannan test (Aspergillus-Ag positive) or a culture of Aspergillus spp. and for whom aspiration (inhalation of food components, e.g. through vomiting) was suspected. With regard to microbiological data: Only information on microbiological data from existing patient files is collected. In the absence of information, no additional samples will be obtained for the study. There is no patient contact.

Exclusion criteria

Exclusion criteria: no specific exclusion criteria

Design outcomes

Primary

MeasureTime frame
Prevalance of invasive fungal diseases in ICU patients

Secondary

MeasureTime frame
Incidence of primary-, secondary- or salvage therapies

Countries

Germany

Contacts

Public ContactSimon Dubler

Universitätsklinikum Heidelberg

simon.dubler@uk-essen.de017631688723

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026