Franconian Cognition and Emotion Studies (FRANCES): Cognitive, emotional and social competencies in primary school age and adolescence: Prenatal risks and developmental outcomes - A prospective cohort study

Franconian Cognition and Emotion Studies (FRANCES): Cognitive, emotional and social competencies in primary school age and adolescence: Prenatal risks and developmental outcomes - A prospective cohort study - FRANCES

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00024729

Enrollment

250

Registered

2021-04-28

Start date

2012-10-08

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

prenatal alcohol exposure prenatal depression and stress psychopathological symptoms in childhood and adolescence

Interventions

Group 1: The children were examined in a longitudinal study at two measurement points (primary school age, adolescence). Child development was assessed in a multi-level design: E.g. cognition and lang

WISC-V), neurophysiological parameters (including event-related potentials), behavior problems (SDQ

DISYPS), cortisol concentrations in saliva and hair, epigenetic data from oral mucosal cells, and inflammatory markers in blood (hsCRP). Data on prenatal risk of children (prenatal alcohol exposure (

Eligibility

Sex/Gender

All

Age

6 Years to 14 Years

Inclusion criteria

Inclusion criteria: Participation in the FRAMES study (Women's Clinic Erlangen)

Exclusion criteria

Exclusion criteria: insufficient/ lack of German language

Design outcomes

Primary

Measure	Time frame
children's/ adolescents' psychopathological symptoms (SDQ, DISYPS-III), state of development (IDS, WISC-V), brain electrical activity (ERPs, Go/NoGo-Task)	—

Secondary

Measure	Time frame
children's /adolescents' stress regulation system (cortisol in hair and saliva), immune system (hsCRP), 2D:4D-ratio, DNA methylation from oral mucosa cells, facial abnormalities in prenatal alcohol exposure	—

Countries

Germany

Contacts

Public ContactAnna Eichler

Universitätsklinikum Erlangen Kinder- und Jugendabteilung für Psychische Gesundheit

anna.eichler@uk-erlangen.de+49 9131 85 44 657

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026