Depth of Anaesthesia
Conditions
Interventions
Group 1: This non-blinded exploratory study recorded intraoperative HRV, Narcotrend Index, and MAC in 31 male patients during radical prostatectomy using the Da-Vinci robotic-assisted surgical system
Sponsors
Universitätsklinikum Mannheim
Eligibility
Sex/Gender
Male
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: Male, undergo a Prostektomy with general Anaesthesia, between 20 and 80 jears of age
Exclusion criteria
Exclusion criteria: Exclusion criteria included age less than 18 and greater than 85 years, diabetes mellitus, ASA status > 2, use of medications affecting the autonomic nervous system, e.g., ß-blockers, antiarrhythmics, and atropine, implantation of a pacemaker, and cardiac arrhythmia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome of the study is to investigate the level of agreement between the HRV parameters (SDNN, RMSSD, HF, LF, LF/HF ratio), the Narcotrend Index of the EEG-based Narcotrend Monitor for the detection of the depth of anesthesia, and the MAC of the inhalation anesthetic sevoflurane across the entire course of surgery. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcome of the study is, that HRV parameters correlate with the Narcotrend Index and reflect central sedation in addition to ANS activity during general anesthesia. | — |
Countries
Germany
Contacts
Public ContactJustus Benrath
Klinik für Anästhesiologie und Operative Intensivmedizin
Outcome results
None listed