Duodenal mast cells and eosinophils in Children with celiac disease: Occurrence and Distribution pattern

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00024669

Enrollment

215

Registered

2021-03-03

Start date

2020-01-10

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K90.0

Interventions

Group 1: Histological re-evaluation of tissue material from celiac patients (counting of mast cells and eosinophils after immunohistochemical staining) Group 2: Histological re-evaluation of tissue ma

Eligibility

Sex/Gender

All

Age

0 Years to 18 Years

Inclusion criteria

Inclusion criteria: Age 0-18 years, Celiac patients: Marsh-score of 3a or higher, controls: normal histopathological evaluation of duodenal mucosa

Exclusion criteria

Exclusion criteria: insufficient amount of duodenal tissue material, Marsh score less than 3a

Design outcomes

Primary

Measure	Time frame
mast cell and eosinophil Counts per High-Power-Field in the lamina propria of celiac patients compared to controls	—

Secondary

Measure	Time frame
distribution pattern of mast cells and eosinophils in the duodenal lamina propria	—

Countries

Germany

Contacts

Public ContactAnjona Schmidt-Choudhury

Kinderklinik Bochum, St. Josef-Hospital

a.schmidt-choudhury@klinikum-bochum.de+49234/5092611

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 14, 2026