F42
Conditions
Interventions
Group 1: CBT-ERM (cognitive-behavioral therapy-exposure with response management) & CBT
Group 2: PDT-ERM & PDT (psychodynamic therapy)
Sponsors
Universitätsklinikum Hamburg-Eppendorf
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: - Presence of a diagnosed obsessive-compulsive disorder (ICD-10: F42 or obsessive-compulsive disorder according to DSM-5 as the primary diagnosis. The diagnosis is made by means of a SKID interview according to DSM-5. - Willingness and consent to participate in the study including randomization (informed consent); ability to give consent - Sufficient knowledge of the German language - Willingness and indication for long-term psychotherapeutic treatment of OCD (long-term psychotherapy, 60 sessions)
Exclusion criteria
Exclusion criteria: - Hoarding disorder - Psychotic disorders according to ICD-10 chapter F2, bipolar disorders (ICD-10 F31 or F34.0) - There must be an indication for primary treatment of the obsessive-compulsive disorder. However, comorbid F-diagnoses do not constitute an exclusion criterion as long as the treatment of the comorbid disease is not a priority.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We use the Yale-Brown Obsessive-Compulsive-Scale (Y-BOCS, Goodman et al., 1989) as the primary outcome which should be collected before the start of treatment (t1), afer 24 therapy sessions (t2), 36 therapy sessions (t3) and 6 (t4) and 12 months (t5) later. As the primary outcome, we define the total score as the metric outcome and the dichotomous outcome response (= 35% symptom reduction) / nonresponse, both measured with the Y-BOCS and remission (Y-BOCS total score = 12). | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes on the patient side are the Obsessive Compulsive Inventory – Revised (OCI-R) as a self-assessment tool and other comorbid symptoms such as depression and anxiety; measured using modules from the Patient Health Questinnaire (PHQ). Further characteristics (possibly) related to obsessive-compulsive symptoms are measured, such as dyfunctional cognition (OBQ-44), Experiential Avoidance (FAH-II), insecurity intolerance (IUS-12) and dealing with aggressiveness (STAXI-II). In addition, the quality of life (SF-12) as well as affective (EBQ) and cognitive mentalization ability (Ment-S, CAMSQ), psychological structure (OPD-SF) are recorded. The secondary endpoints are also recorded before the starte of treatment (t1), after 24 therapy sessions (t2), 36 therapy sessions (t3) and 6 (t4) and 12 months (t4) later. Traumatic experiences are recorded using CTQ before the first interview (t0). Side effects of psychotherapy are recoredet with the INEP, on the one hand before the initial consultation if psychotherapeutic treatments have already taken place, on the other hand after the end of therapy and at the time of the follow-up measurements in order to assess possible side effects of the psychotherapy carried out in the context of the study. On the therapist side, we intend to measure the therapeutic relationship with the Berner Psychotherapy Session Questionnaire and the WAI, processes with the Comparative Psychotherapy Process Scale (CPPS), and adherence and competence with a specially developed instrument. | — |
Countries
Germany
Outcome results
None listed