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Is there a circadian differential effect of fatigue in multiple sclerosis (MS) on sustained attention performance and EEG frequency patterns?

Is there a circadian differential effect of fatigue in multiple sclerosis (MS) on sustained attention performance and EEG frequency patterns?

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00024516
Enrollment
40
Registered
2021-02-18
Start date
2021-02-26
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fatigue in multiple sclerosis G35

Interventions

Group 1: Multiple sclerosis patients with fatigue (FSMC cognitive score = 22): first we will use VAS to measure subjective cognitive fatigue, perceived stress due to testing, and stress due to rehabil

Sponsors

Carl von Ossietzky Universität Oldenburg, Department für Psychologie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: - a clinically diagnosed MS - minimum age of 18 years

Exclusion criteria

Exclusion criteria: - An MS-independent psychiatric disorder that was already known before the diagnosis of MS, i.e. does not have to be considered a direct or indirect consequence of MS. - Psychoactive medication (noradrenergic antidepressants, modafinil or amantadine). - Methylprednisolone relapse therapy within the last 4 weeks. - No sufficient success during the vigilance test, e.g. as a result of a strong decrease of visual acuity, etc.

Design outcomes

Primary

MeasureTime frame
Performance on the vigilance test will serve as the primary outcome parameter. We expect a difference between the groups (multiple sclerosis with or without fatigue) in the afternoon and not in the morning.

Secondary

MeasureTime frame
The secondary outcome parameters are VAS and EEG frequency spectrum.

Countries

Germany

Contacts

Public ContactAlja Bernik

Carl von Ossietzky Universität Oldenburg, Department für Psychologie

alja.bernik@uni-oldenburg.de0038631542502

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026