Randomized controlled pilot study on the effect of combined vibration and sensorimotor training on persistent chemotherapy-induced polyneuropathy in cancer survivors

Randomized controlled pilot study on the effect of combined vibration and sensorimotor training on persistent chemotherapy-induced polyneuropathy in cancer survivors - VIBRANCY-Study

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

DRKS

Registry ID

DRKS00024514

Enrollment

Registered

2021-06-04

Start date

2021-08-18

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C00-C97

Interventions

Group 1: Combined whole-body vibration and sensorimotor training (12 weeks) Group 2: Waiting control group - Combined whole-body vibration and sensorimotor training (12 weeks)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients within follow-up after malignant cancer (all entities); completion of medical system therapy (chemotherapy) at least 6 months ago; patients with existing CIPN (anamnesis); age = = 18 years.

Exclusion criteria

Exclusion criteria: Palliative patients or patients with advanced cancer; patients undergoing acute cancer therapy; polyneuropathy of other etiologies (diabetes mellitus, alcohol abuse, etc.); medications that cause polyneuropathy; participation in another study involving exercise intervention; medical conditions that compromise patient safety or study feasibility.

Design outcomes

Primary

Measure	Time frame
Reduction of CIPN (EORTC-QLQ-CIPN20) baseline (week 0) versus post assessment (week 12)	—

Secondary

Measure	Time frame
CIPN (Common Terminology Criteria for Adverse Events (CTCAE), Peripheral deep sensitivity (Tuning fork), Leeds Assessment of Neuropathic Symptoms and Signs (LANSS), Numeric Rating Scale), coordinative performance (Single Leg Stance, Short Physical Performance Battery, SPPB), physical activity (Bewegungs- und Sportaktivität Fragebogen, BSA-Fragebogen), quality of life (EORTC-QLQ-C30), feasibility	—

Countries

Germany

Contacts

Public ContactJannike Salchow

Universitätsklinikum Hamburg-Eppendorf

j.salchow@uke.de+4940741057355

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026