M17
Conditions
Interventions
Group 1: Group 1: Lower extremity strength training (Burrows et al., 2014
Kampshoff et al., 2018):
o Dosage: 50-70% of 1RM (Borg 12-13), 3 sets of 10 repetitions with 1,5 minutes rest between sets.
o Exercises: Leg curlers, knee extensors, hip abductors.
o Substitute exerc
Kampshoff et al., 2018):
o Dosage: 50-70% of 1RM (Borg 12-13), 3 sets of 10 repetitions with 1,5 minutes rest between sets.
o Exercises: Lat pulldown, chest press, cable rowing
o Substitute exercises
Jones et al., 2017).
o Dosage: 5-minute warm-up (Borg 8), then increased resistance towards Borg 12-13 for a duration of 20 minutes.
o Exercise: bicycle ergometer
o Substitute exercise: walking on a
Sponsors
Hochschule für Gesundheit
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - People suffering from unilateral or bilateral osteoarthritis of the knee (symptomatic or asymptomatic) that has been medically diagnosed () osteoarthritis of the knee (according to ICD-10 polyarthrosis M.15, osteoarthritis of the knee M17)
Exclusion criteria
Exclusion criteria: - Patients who are on a waiting list for a total joint replacement of the knee, who already have a firm appointment for such a surgery, or whose affected knee joint has already been replaced - uncertainty regarding eligibility for physical training and no physician's consent regarding eligibility for physical training. Risk stratification by the Physical Activity Readiness Questionnaire (PAR-Q) - The presence of other pain problems associated with subjectively more severe pain than the knee pain - Addictive behavior to opioids (or other pain medications) - Presence of relevant secondary diagnoses, which include the following: Neurological disorders (e.g., multiple sclerosis, post-stroke condition, or Parkinson's disease), Rheumatic diseases (e.g. rheumatoid arthritis or fibromyalgia), Unstable health condition (e.g., cancer, dialysis, or acute trauma), Cognitive impairment (e.g., dementia), Serious psychological illness (e.g., major depression)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome is the evaluation of the feasibility. For this purpose, the study design, the required resources, the measurement method and the intervention are examined using defined criteria for successful implementation. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcome of this study is the magnitude of the EIH response as measured by pre-post differences in pressure pain threshold (PPT). PPT will be measured bilaterally at three different body sites (descending trapezius muscle, rectus femoris muscle, medial compartment of the knee joint) using a digital pressure algometer (SB Medic, Solna, Sweden). On each measurement day, the measurement of the body sites takes place immediately before and after the training session and 30 minutes after the end of the training session. Each body site will be measured three times each time. The average value of the three measurements per body site will be used for analysis. As a measure of EIH, the PPT values at post measurement (based on the pre-post differences: PPT2 minus PPT1 and PPT3 minus PPT1) will be assessed. | — |
Countries
Germany
Contacts
Public ContactMarie-Sofie Anderheide
Hochschule für Gesundheit
Outcome results
None listed