Comparison of different modes of non-invasive activation of the diaphragm

Comparison of different modes of non-invasive activation of the diaphragm - MSD (Magnetic stimulation of the diaphragm)

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00024449

Enrollment

Registered

2021-05-07

Start date

2022-02-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breathing mechanics of healthy volunteers

Interventions

Group 1: Application of each 3 different modes of non-invasive stimulation of the diaphragm in each participating subject: - transcranial magnetic stimulation - transcervical magnetic stimulation - ce

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - =18 years of age; - Signed informed consent; - absence of a legal guardian;

Exclusion criteria

Exclusion criteria: Acute or chronic severe neurologic or respiratory disease; acute or chronic severe systemic disease; contraindication for applying transcranial magneteic stimulation (epilepsy, metallic implants within or close to the head, pace-maker)

Design outcomes

Primary

Measure	Time frame
Measurements of amplitude and latency of motor-evoked potentials of the diaphragm depending on the type of stimulation	—

Secondary

Measure	Time frame
Intensity of stimulation necessary to evoke motor responses; degree of coactivation of other muscles	—

Countries

Germany

Contacts

Public ContactCaspar Stephani

Universitätsklinikum Göttingen Klinik für Anästhesiologie und Klinik für Neurologie

CStephani@med.uni-goettingen.de+49-551-39-67744

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026