Functional connectivity changes in multisensory cortical areas in patients with spatial neglect treated with subliminal galvanic vestibular stimulation

Functional connectivity changes in multisensory cortical areas in patients with spatial neglect treated with subliminal galvanic vestibular stimulation - GSTIM-NFC

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

DRKS

Registry ID

DRKS00024442

Enrollment

120

Registered

2021-02-09

Start date

2019-10-11

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I63.9 R29.5

Interventions

Group 1: subliminal stimulation cathode right (CR) time points: Time point: d0 - Inclusion / exclusion criteria - informed consent - randomization Neglect tests: - Bells test - Line bisection test

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1st ever ischemic or hemorrhagic stroke (lacunar infarcts are tolerable) Age > 18. LJ Capacity to consent Ability to complete study investigations Neglect Group: Neglect group (one or more of the following findings): Gaze preference to the side of the lesion. Impaired visuospatial and motor - exploration in the contralesional space. Inability to respond to stimuli in the contralesional space At least 2 abnormal neglect tests

Exclusion criteria

Exclusion criteria: Multiple strokes / history of stroke (except small lacunes) brainstem / cerebellar infarcts extensive vascular leukencephalopathy (Fazekas >II) respiratory / cardiac insufficiency edema (displacement of midline structures, compression of CSF spaces) neurodegenerative disease (MoCA<20) Acute psychiatric disease with limited insight Active tumor with life expectancy <1 year skin irritation around the mastoid Epilepsy (except symptomatic "early seizures") previous disorder of the vestibular system with permanent dysfunction of the vestibular endorgans Cardiac pacemaker Brain pacemaker non-MRI-capable metal parts after surgery cardiac stents < 3 months shrapnel large tattoos

Design outcomes

Primary

Measure	Time frame
compensation of spatial neglect using paper / pencil neglect tests, Catherine Bergego scale, test battery for attention testing (TAP) after three weeks of treatment with subliminal GVS	—

Secondary

Measure	Time frame
functional connectivity changes in multisensory vestibular, visual and dedicated attention network (ventral / dorsal attention network)	—

Countries

Germany

Contacts

Public ContactCarmen Krewer

Schön Klinik Bad Aibling

CKrewer@schoen-klinik.de+49 8061 903-0

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026