Healthy controls SARS-CoV-2 vaccinated chronic inflammation
Conditions
Interventions
Group 1: Patients with chronic inflammatory diseases (CID) SARS-CoV-2 vaccinated:
Blood samples will be analysed before and at several timepoints after the vaccination. Cellular components like B cel
Sponsors
UKSH Kiel/1. medizinische Klinik/Rheumatologie
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: a SARS-CoV-2 vaccination is planned. In addition, one of the following diseases: standard criteria (ACR/EULAR) for diagnosed Rheumatoid arthritis, spondyloarthorpathy, vasculitis or collagenosis. Gastroenterological diagnosed chronic inflammatory bowel disease (Morbus Crohn or Colitis Ulcerosa), Dermatologically confirmed Psoriasis. For the control group, the mentioned diseases are exclusion criteria. In addition, written informed consent is needed.
Exclusion criteria
Exclusion criteria: maligne disease, other autoimmune diseases (with immunosuppressive therapy), Infections (e.g. HIV, Hep C, Hep B) Age under 18 years, lacking capacity to consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Antibodies against SARS-CoV-2 can be measured 1 week after the second immunisation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Antibodies against SARS-CoV-2 can be measured 6 months after the second immunisation. | — |
Countries
Germany
Contacts
Public ContactBimba Franziska Hoyer
UKSH Kiel/1. medizinische Klinik/Rheumatologie
Outcome results
None listed