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Implementation of the KDIGO guidelines for the prevention of AKI in patients after cardiac surgery – an international multicenter observational trial

Implementation of the KDIGO guidelines for the prevention of AKI in patients after cardiac surgery – an international multicenter observational trial - 02-AnIt-20

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00024204
Enrollment
500
Registered
2021-01-29
Start date
2021-02-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

N17

Interventions

Group 1: All patients will be assessed for their medical history, postoperative renal function and implemented measures of care. All data will be extracted from the medical records. Preoperative data

Sponsors

Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Adult patients undergoing cardiac surgery with CPB 2. Age between 18-90 years 3. Written informed consent

Exclusion criteria

Exclusion criteria: 1. Preexisting AKI (stage 1 and higher) 2. Patients with cardiac assist devices (ECMO, LVAD, RVAD, IABP) 3. Pregnancy, breastfeeding 4. Known (Glomerulo-) Nephritis, interstitial nephritis or vasculitis 5. Chronic kidney disease (CKD) with eGFR < 20 ml/min/1.73m2 6. Dialysis dependent CKD 7. Prior kidney transplant within the last 12 months 8. Persons held in an institution by legal or official order 9. Persons with any kind of dependency on the investigator or employees by the investigator

Design outcomes

Primary

MeasureTime frame
To assess the adherence to the preventive care bundle according to the KDIGO guidelines in patients undergoing cardiac surgery with cardiopulmonary bypass

Secondary

MeasureTime frame
- occurrence of AKI within 72 hours after cardiac surgery - severity stage of AKI within 72 hours after cardiac surgery - use and duration of renal replacement therapy (RRT) - length of ICU stay - length of hospital stay - MAKE30 (combined endpoint consisting of persistent renal dysfunction (defined as serum creatinine = 1.5-times baseline), RRT and mortality) at day 30)

Countries

Germany, Russia, Spain

Contacts

Public ContactChristina Massoth

Klinik für Anästhesiologie, operative Intensivmedizin und Schmerztherapie, Universitätsklinik Münster

Christina.massoth@ukmuenster.de+49 251 83 47282

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 9, 2026