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Dexmedetomidine versus sufentanil as adjuvants to bupivacaine on the onset and duration of brachial plexus block in patients undergoing upper extremity surgery

Dexmedetomidine versus sufentanil as adjuvants to bupivacaine on the onset and duration of brachial plexus block in patients undergoing upper extremity surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
DRKS
Registry ID
DRKS00024182
Enrollment
40
Registered
2021-01-29
Start date
2019-10-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Comparing clinical (theraputic) efficacy of two drugs.

Interventions

Group 1: Group S that received 1 mL of 5µg/1mL sufentanil added to 30 mL of 0.5% bupivacaine via single supraclavicular injection under the ultrasonography guidance. The used sufentanil is a product o

Sponsors

Aja University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients with American Society of Anesthesiologists (ASA) class 1 and 2 Aged between 20 and 65 years Scheduled for elective upper limb surgeries

Exclusion criteria

Exclusion criteria: Patients outside the age range of the study Patients with the history of brachial plexus injury Patients with the history of allergic reactions to study drugs

Design outcomes

Primary

MeasureTime frame
The duration of sensory block: The time interval between the start of the complete sensory block and its full restoration to the normal state, Measurement intervals: for the first 12 hours after the injection, every 2 hours; and every 1 hour for the rest of the study. Measurement method: Using pinprick test compared with the non-injured upper limb

Secondary

MeasureTime frame
1)The duration of motor block: The time interval between the start of the complete motor block and its full restoration to the normal state Measurement intervals: For the first 12 hours after the injection, every 2 hours; and every 1 hour for the rest of the study Measurement method:Motor block was evaluated using modified Lovett’s rating scale; 2)The onset of sensory block: The time interval between the completion of injection and the resultant complete sensory block was defined as the onset of sensory block Measurement intervals: For the first 15 minutes post-injection: every 3 minutes; and every minute till the completion of the sensory block Measurement method: Using pinprick test compared with the non-injured upper limb; 3)The onset of motor block: The time interval between the completion of injection and the resultant complete motor block was defined as the onset of sensory block Measurement intervals: For the first 15 minutes post-injection: every 3 minutes; and every minute till the completion of the motor block Measurement method: Motor block was evaluated using modified Lovett’s rating scale ; 4)Total postoperative opioid (intravenous morphine sulfate) consumption in the first 24 hours Measurement intervals: At the end of the first 24 hours after the surgery Measurement method: By using patients’ folders and nursing notes; 5)The first opioid (intravenous morphine sulfate) request time Measurement intervals:Within 24 hours after surgery Measurement method: By using patients’ folders and nursing notes; 6)Pain level Measurement intervals:Pain levels were recorded at 30, 15, 10, and 5 minutes before, once during, and 6, 12, 18, and 24 hours after the surgery Measurement method:By using Visual Analog Scale; 7)Mean arterial (blood) pressure Measurement intervals: At the anesthetic injection time, 5, 15, and 30 minutes after the injection and every 15 minutes until the end of surgery Measurement method:By using patient monitoring device; 8)Respiratory rate Measu

Countries

Iran

Contacts

Public ContactEbrahim Hazrati

Aja University of Medical Sciences

dr.hazrati.e@gmail.com+98 912 381 0956

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026