Consequences of menopause: weight gain, altered body composition, altered fat metabolism, altered bone metabolism.
Conditions
Interventions
Group 1: Subjects who receive no training and no protein supplementation. The study is designed so that the control group will be without training and protein supplementation for 3 month. After 3 mont
Sponsors
Deutsche Sporthochschule Köln, Institut für Kreislaufforschung und Sportmedizin, Abtl. Molekulare und zelluläre Sportmedizin
Eligibility
Sex/Gender
Female
Age
50 Years to 65 Years
Inclusion criteria
Inclusion criteria: postmenopausal women (50-65 years) - at least 2 years after the last menstrual period - willingness to use fitness tracker "Polar Ignite" and Polar Flow app
Exclusion criteria
Exclusion criteria: - > 2 times endurance training per week - Unbalanced diets (e.g. vegan) - Hormone substitution (incl. oral contraceptives) - Hormonal diseases - Psychiatric and / or addictive disorders - Heart failure (EF <55) - Metabolic diseases - Cardiac arrhythmias requiring treatment - Performance-limiting neurological diseases - Performance-limiting renal disease - Performance-limiting biliary disease - Performance-limiting gastrointestinal diseases - Performance-limiting pAVK (Fontaine stage = II) - Performance-limiting muscular diseases - Performance-limiting degenerative diseases - Performance-limiting respiratory diseases - History of performance-limiting oncological diseases (< 5 years)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Data will be collected at the start of the first training period, at the end of the first training period, and at the end of the second training period. Collected are: by means of blood sampling - estradiol - progesterone - FSH - MYO before and after exercise - Blood glucose before and after exercise - HBa1c long-term blood glucose value - HDL - LDL - triglycerides - d44Ca/42Ca as proxy for bone metabolism By means of a step test - Individual anaerobic threshold - Watts - HR - lactate - 13C/12C in expired CO2 - d 13C/12C, Delta over Baseline (DOB) - oxygen uptake - Carbon dioxide output - Respiratory quotient (RQ) - Caloric equivalent by morning urine - d44Ca/42Ca as a proxy for bone metabolism | — |
Secondary
| Measure | Time frame |
|---|---|
| Data will be collected at the start of the first training period, at the end of the first training period, and at the end of the second training period. Collected are: - Body height in cm - weight in kg by means of BIA: - Body fat mass - body cell mass - body water - lean mass - muscle mass - Extracellular mass by means of strength testing: - Leg press 5RM - Chest press 5RM - Grip strength 5RM By means of Polar watch Ignite - Number of steps per day - Heart rate during training sessions - Sleep behavior by means of sleep index by questionnaire: - Physical activity behavior | — |
Countries
Germany
Contacts
Public ContactKatharina Brück
Deutsche Sporthochschule Köln – German Sport University Cologne, Institut für Kreislaufforschung und Sportmedizin, Abtl. Molekulare und zelluläre Sportmedizin
Outcome results
None listed