Dystonia
Conditions
Interventions
Group 1: Patients with Dystonia, who received misplaced DBS electrodes in the mesitemporal region (these data already exist), who received neuropsychological testing under three different stimulation
Sponsors
Universitätsklinik für Neurologie, Evangelisches Krankenhaus Oldenburg Abteilung für Neurologie, Fakultät für Medizin und Gesundheitswissenschaften, Carl von Ossietzky Universität Oldenburg
Eligibility
Sex/Gender
Female
Age
35 Years to 65 Years
Inclusion criteria
Inclusion criteria: Dystonia patients will be included, if they have received DBS in the GPi, if they match the age range of 35-65 years and if they are female. Further, a pre-operative MRI or CT is required to locate the placement of electrodes using lead DBS.
Exclusion criteria
Exclusion criteria: Patients will be excluded from the study, if thy show any kind of cognitive impairment and/or if the electrode was not correctly placed in the GPi, according to LeadDBS.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The goal of this study is to provide a control group for already existing and also ethically approved data. To see whether the results can be replicated by stimulating correctly placed electrodes of the GPi, comparable cases need to be provided. The proposed study is considered purely experimental and is not aimed to give any therapeutic insight. Cognitive Performance is measured using four neuropsychological tests: Word-Pair learning, Digit ordering, stroop task and verbal fluency. All tests are done on three days under different stimulation conditions (no stimulation, 20Hz and 120 Hz Stimulation). | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome are neurological examination and a wellbeing questionnaire. | — |
Countries
Germany
Contacts
Public ContactCharlotte Büttner
Abteilung für Neurologie, Fakultät für Medizin und Gesundheitswissenschaften, Carl-von-Ossietzky Universität Oldenburg
Outcome results
None listed