"Cerebrospinal Fluid Analysis in Psychiatry" - Multicentric, prospective patient registry for cerebrospinal fluid analysis in psychiatric patients

"Cerebrospinal Fluid Analysis in Psychiatry" - Multicentric, prospective patient registry for cerebrospinal fluid analysis in psychiatric patients - CAP

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00024041

Enrollment

200

Registered

2021-02-18

Start date

2021-02-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ICD-10 F*: Mental and behavioral disorders

Interventions

Group 1: Non-interventional

prospective observational study, non-randomized. Collection of biomaterials (CSF, blood, serum) and recording of patient data. Consisting of two groups of patients: 1. patients who have a mental and/o

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1) Patients who have a mental and/or behavioral disorder (ICD-10 F*) and receive a lumbar puncture (i.e., a medical procedure to collect cerebrospinal fluid) as part of the diagnosis; 2) Control group: Patients whom CSF is analyzed due to a neurological exclusion diagnosis (e.g., in case of headache) and in whom a mental and/or behavioral disorder (ICD-10 F*) has been excluded; 3) Age = 18 years; 4) Informed consent that is signed by the patient or his/her legal caregiver/supervisor

Exclusion criteria

Exclusion criteria: 1) Patients who are unable to consent, who do not understand the background and significance and consequences of the study, or whose legal caregiver/supervisor is unwilling to consent; 2) Control group: psychiatric disease (ICD-10 F*)

Design outcomes

Primary

Measure	Time frame
Prevalence and type of CSF abnormalities occurring in psychiatric patients, as well as the provision of data for further scientific investigations. Development of guidelines for CSF analysis in psychiatry and thus an improvement of the current diagnostic practice and health care for patients with neuropsychiatric diseases.	—

Secondary

Measure	Time frame
1. Collecting the following data: a) indication of the lumbar puncture, b) prevalence and unwanted adverse reactions of the lumbar puncture, c) type and frequency of pathological CSF abnormalities; 2. Identifying biomarkers in CSF and serum	—

Countries

Germany

Contacts

Public ContactAlexandra Neyazi

Klinik für Psychiatrie, Sozialpsychiatrie und Psychotherapie, Medizinische Hochschule Hannover

neyazi.alexandra@mh-hannover.de+49 511 5323656

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026