C00-C97
Conditions
Interventions
Group 1: Cancer-patients of which the diagnostic and therapeutic management was discussed in the Molecular (Tumor) Board (MTB) of the University Hospital Tübingen. For the patients, a PET/CT examinati
Sponsors
Universitätsklinikum Tübingen
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: • Presence of a tumor disease and presentation of the patient in the Molecular Tumor Board (MTB) of the University Hospital Tübingen • Performing a PET/CT based on a clinical indication (MTB) • The patient tolerates about 60 minutes of lying in the tomograph • Age =18 years • Written consent from the patient
Exclusion criteria
Exclusion criteria: • Pregnant / breastfeeding women • Presence of non-MR compatible implants or any kind of metal in and on the body • Patients who report a hearing impairment or an increased sensitivity to loud noises • Patients with limited temperature sensation • Claustrophobia • Limited ability to give consent • Obesity with a body weight of> 150 kg • No consent to the communication of incidental findings
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Collection of 50 tumor patient-related image data sets, consisting of morphological and functional PET/MRI image data of the primary tumor. The image data are correlated with existing corresponding histopathological and molecular biological information with the aim of developing image-based marker sets for molecular tumor characterization. | — |
Secondary
| Measure | Time frame |
|---|---|
| • Tumor subtyping based on multiparametric image data with regard to prognosis and prediction factors such as receptor status, TNM grading • Correlation and voxel-by-voxel analysis of the PET/MRI data sets with corresponding molecular (bio) markers with the aim of mapping three-dimensional "maps" of various functional and morphogenetic parameters • Development and clinical application of machine learning approaches, e.g. for texture analysis | — |
Countries
Germany
Contacts
Public ContactFerdinand Seith
Radiologische Universitätsklinik Tübingen Diagnostische & Interventionelle Radiologie
Outcome results
None listed