Antiseptic gargle in COVID-19

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00024028

Enrollment

Registered

2021-02-11

Start date

2021-01-24

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

U07.1

Interventions

Group 1: No intervention (standard of care) Group 2: Gargling 3 times daily for 60 seconds each with chlorhexidine/ethanol solution

Eligibility

Sex/Gender

All

Age

18 Years to 110 Years

Inclusion criteria

Inclusion criteria: Hospital admission at University Hospital Rostock and positive SARS-CoV-2 PCR (specimen from oropharyngeal swab), consent to participate

Exclusion criteria

Exclusion criteria: Pregnancy, past or current alcohol dependence, intolerance of chlorhexidine

Design outcomes

Primary

Measure	Time frame
Time from initial positive SARS-CoV-2 PCR (from nasopharyngeal swab) until first of two negative specimen (specimens are taken every 2-3 days).	—

Secondary

Measure	Time frame
Course of oxygen saturation (pulse oximetry), oxygen flow through nasal cannula, invasive or non-invasive ventilation, admission to intensive care unit, time until symptom-free, death, known secondary infections by study participant	—

Countries

Germany

Contacts

Public ContactCarlos Fritzsche

Abteilung für Tropenmedizin und Infektionskrankheiten Zentrum für Innere Medizin, Universitätsmedizin Rostock

carlos.fritzsche@med.uni-rostock.de0381-494 7514

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026