Airway colonization with Pseudomonas aeruginosa in chronic obstructive pulmonary disease (COPD)/non-CF bronchiectasis - an observational and biomaterial study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00023975

Enrollment

Registered

2020-12-28

Start date

2020-11-12

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

J44.9 J47 B96.5

Interventions

Group 1: Patients with COPD and/or non-CF bronchiectasis and detected airway colonization by P. aeruginosa: observation of disease course over a period of 1 year (registration of clinical parameters)

collection of biomaterial (sputum, nasopharyngeal and rectal swabs) for microbiological characterization of colonizing pseudomonas isolates and characterization of the airway and gut microbiome.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Diagnosis of COPD and/or non-CF bronchiectasis with exacerbation; Detection of airway colonization by P. aeruginosa

Exclusion criteria

Exclusion criteria: Pregnancy/breast feeding; diagnosis of cystic fibrosis (CF); inherited or acquired immune deficiency

Design outcomes

Primary

Measure	Time frame
Descriptive: Success of antibiotic eradication therapy of P. aeruginosa	—

Secondary

Measure	Time frame
Explorative and ex vivo-experimental analysis of obtained biomaterial	—

Countries

Germany

Contacts

Public ContactBarbara Kalsdorf

Forschungszentrum Borstel Medizinische Klinik

studienzentrum@fz-borstel.de+49 4537 1880

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: May 23, 2026