Perioperative cardiovascular events
Conditions
Interventions
Group 1: On the day of the indication for a vascular surgical operation, study patients are ordered statins in accordance with the guidelines and blood is taken to quantify the Tregs, provided there i
Sponsors
Universitätsklinikum Essen
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Consent, 18 years or older, planned start of preoperative statin therapy, elective, inpatient vascular surgery within the next 28 days
Exclusion criteria
Exclusion criteria: Statin therapy within the past 28 days, pregnancy, breastfeeding, contraindication to statin therapy, condition after splenectomy, myocardial infarction, stroke or acute heart failure diagnosed in the past 28 days
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference in the number of regulatory T cells circulating in the blood between baseline (before starting statin therapy) and the day of surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Death, cardiovascular death, myocardial ischemia, myocardial infarction, MINS (myocardial injury after non cardiac surgery) ischemic stroke, new heart failure, new atrial fibrillation, length of intensive care stay and length of hospital stay. | — |
Countries
Germany
Contacts
Public ContactFlorian Espeter
Klinik für Anästhesiologie und Intensivmedizin Universitätsklinikum Essen
Outcome results
None listed