Dose reduction of CT perfusion in patients with acute stroke by optimizing the timing of acquisition time

Dose reduction of CT perfusion in patients with acute stroke by optimizing the timing of acquisition time - CT-Brain-Reduce-Dose

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00023941

Enrollment

Registered

2021-07-28

Start date

2021-04-10

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I64

Interventions

Group 1: DICOM data of CT perfusion will be extracted from the institutional PACS, imaging data will be anonymized. Simulated dose reduced CT perfusion examinations will be generated by reducing the n

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with symptoms of an acute stroke receiving non enhanced cranial CT, CT angiography of the carotid aretry including an archived bolus tracking serie and a CT perfusion on the institutional CT scanner Somatom Force Siemens Healthineers. Patients with documented acut ischemic stroke.

Exclusion criteria

Exclusion criteria: Non valid CT perfusion. Significant altered fluss injection rate of contrast agent in CT perfusion and CT angiography of the carotid artery.

Design outcomes

Primary

Measure	Time frame
Reduction of radtion exposure by 20 %.	—

Secondary

Measure	Time frame
In the qualitative evaluation of dose reduced simulated CT perfusion examinations, the lowering of the number of scans should have no significant influence on „change of management“ for patient care.	—

Countries

Germany

Contacts

Public ContactChristel Besseler

Klinik und Poliklinik für Radiologie Klinikum der Universität München Campus Großhadern

christel.besseler@med.uni-muenchen.de(089) 4400-73647

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026