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The link between physical fitness and the reward system in schizophrenia

The link between physical fitness and the reward system in schizophrenia - FRS

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00023907
Enrollment
100
Registered
2021-02-03
Start date
2021-02-26
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F20-F29

Interventions

Group 1: Schizophrenic patients: Examination of the reward system using fMRI, examination of physical fitness using anthropometric measurement, examination of psychopathology using interviews (PANSS)

Sponsors

Klinik für Psychiatrie, Psychosomatik und PsychotherapieUniversitätsklinikum Frankfurt
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: stable medication regime, regular and long antispychotic intake

Exclusion criteria

Exclusion criteria: pregnancy, use of amphetamines or cocaine within the last four weeks, no relevant clinical neurologycal illness MRI contraindications: fever, pacemakers, infusion pumps, metal plates, screws (e.g. after a bone fracture), implants, protheses (e.g. shunts, stents aneurysm clips), injuries with metaldust or shrapnel, tattoos or permanent makeup, pregnancy, IUD (intrauterine device), claustrophobia, dentures, dental implants, bridges, braces or retainers (which are not removable) In addition piercings and nicotine patches must be removed, the same applies to hearing aids, removable braces dentures and soft contact lenses. Bras with metal parts should be removed. The subject should not wear any make up.

Design outcomes

Primary

MeasureTime frame
rewardsystem measured in the striatum, one time measurement, MRI (fMRI-BOLD-response)

Secondary

MeasureTime frame
physical fitness test , anthropometric measures e.g. Chester-Step-Test

Countries

Germany

Contacts

Public ContactOliver Grimm

Klinik für Psychiatrie, Psychosomatik und PsychotherapieUniversitätsklinikum Frankfurt

oliver.grimm@kgu.de+496963014784

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026