Incidence of paraproteinemic keratopathy in patients with monoclonal gammopathy of undetermined significance, smoldering multiple myeloma und multiple myeloma

Incidence of paraproteinemic keratopathy in patients with monoclonal gammopathy of undetermined significance, smoldering multiple myeloma und multiple myeloma - PPK-Study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00023893

Enrollment

100

Registered

2021-01-11

Start date

2018-01-04

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

D47.2 C90.01

Interventions

Group 1: Patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering multiple myeloma (SMM), or multiple myeloma (MM) are examined ophthalmologically to investigate ocular invo

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Patients diagnosed with monoclonal gammopathy of unclear significance (MGUS), smoldering multiple myeloma (SMM) or multiple myeloma (MM) men and women - Age = 18 years - The patient is able to participate in the course of the study - The patient is able to give consent and has consented to participate in the study.

Exclusion criteria

Exclusion criteria: - Condition after bilateral refractive corneal surgery (e.g. LASIK, LASEK, PTK) - Patients with no measurable M protein in urine or serum - Patients with asecretory multiple myeloma - plasma cell leukemia

Design outcomes

Primary

Measure	Time frame
Description of the prevalence of paraproteinemic keratopathy	—

Secondary

Measure	Time frame
Interrelation between the ophthalmological and hematological findings in paraproteinemic keratopathy	—

Countries

Germany

Contacts

Public ContactJoanna Wasielica-Poslednik

Klinik und Poliklinik für Augenheilkunde der Universitätsmedizin Mainz

joanna.wasielica-poslednik@unimedizin-mainz.de+49 (0) 6131 17-7062

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 11, 2026