Microcirculation disorders after blood loss, volume shift or during single lung ventilation
Conditions
Interventions
Group 1: In patients receiving surgery with expected blood loss >500ml or large volume shifts or single lung ventilation, measurements of the digital and manual recapillarization time as well as laser
Sponsors
Klinik & Poliklinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Carl Gustav Carus Dresden
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Declaration of consent of the patients - Age over 18 years - Sinus Rhythm - Ability to give consent - Planned major surgical intervention in visceral/thoracic surgery, urology or orthopedics/accident surgery under general anesthesia with expected major blood losses =500ml - Necessary application of an invasive arterial blood pressure measurement
Exclusion criteria
Exclusion criteria: - Refusal - Pacemaker - higher grade valvular disease - BMI =30 kg/m2 - Peripheral arterial occlusive disease - Raynaud's disease - Existing catecholamine needs - Intraoperative equipping of an epidural catheter - Septic patients - Chron. Skin diseases - Allergy to Propofol/Soya/Rocuronium - Contraindication for inhalative anesthesia - Extensive injuries/burns/ bandages on forearms, feet/ hands/ forehead/ chest - Rheumatism or diseases of the rheumatoid form - Varicosis at the site to be examined - Preoperative use of vasodilatory drugs - Pre-operation on body areas to be examined - Pronounced edema in the body parts to be examined
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| -acquisition of the digital CRT at rest / during / after anaesthesia and after blood loss >500ml or during single lung ventilation | — |
Secondary
| Measure | Time frame |
|---|---|
| - intensity of pain during the operation - CRT on different parts of the body - Lactate, pO2, cardiac output changes under single lung ventilation, after blood loss >500ml | — |
Countries
Germany
Contacts
Public ContactRosa Nickl
Klinik & Poliklinik für Anästhesiologie uund Intensivmedizin, Universitätsklinikum Carl Gustav Carus Dresden
Outcome results
None listed