Investigation of the role of cytokines, chemokines and their receptors in the inflammatory process in asthma patients

Investigation of the role of cytokines, chemokines and their receptors in the inflammatory process in asthma patients - AZCRA

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00023843

Enrollment

Registered

2020-12-17

Start date

2020-10-01

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

J45

Interventions

Group 1: Healthy and asthmatic individuals Sample collection: - Blood taking - 2 Nasal swabs - lung function measurement - questionnaire

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: healthy controls without Asthma or allergies in good general health condition. Asthmatic patients with and without immunotherapy with stable status of their Asthma bronchiale.

Exclusion criteria

Exclusion criteria: -severe, instable Asthma -other chronic respiratory diseases except for allergic Rhinitis -other chronic diseases or Long-term medication except for atopic eczema

Design outcomes

Primary

Measure	Time frame
The aim of this study is to have a better understanding of the regulatory role of cytokines, chemokines and their receptors in Asthma. They are often overexpressed in allergic Asthma. In cell culture Experiments PBMC are treated with different Stimuli and their gene Expression will be analyzed.	—

Secondary

Measure	Time frame
The data from this study should be used to gain new approaches and targets for Asthma therapy.	—

Countries

Germany

Contacts

Public ContactSusetta Finotto

Molekulare Pneumologie Universitätsklinikum Erlangen

susetta.finotto@uk-erlangen.de09131 85 42454

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 11, 2026