Social Influence on acute and chronic pain in women - an fMRI study

Social Influence on acute and chronic pain in women - an fMRI study - SiP-fMRI

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00023753

Enrollment

120

Registered

2021-03-18

Start date

2021-04-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic/recurrent pelvic pain, dysmenorrhea, endometriosis N94.4 N94.5 N80 R10.2 N94.6

Interventions

Group 1: Sample The clinical group will consist of 60 patients with chronic pelvic pain, possibly caused by endometriosis. They will be recruited mainly through the department of Gynecologic Endocrino

Henze, Konzok, Kreuzpointner, Bärtl, Peter, Giglberger, et al. 2020). We will use a Siemens, Erlangen, 3 Tesla MAGNETOM Trio Prima Fit for magnetic resonance imaging. In order to measure the heart rat

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: • chronic/recurrent pelvic pain • suspicion of endometriosis • Patients must be able to specify a range of maximally 7 days with regard to their next menstrual onset.

Exclusion criteria

Exclusion criteria: • long-cycle treatment with oral contraceptives • current or preceding neurological • current psychotic disorder • current psychopharmacological treatment • psychoactive medication, preceding alcohol abuse or substance abuse • chronic cardiovascular disease • pacemaker or other inlying/ external medical devices • metal implant or metal foreign objects • current pregnancy or lactation • current hormonal fertility treatment • cancer of the breast, cervix or ovary • other types of cancer • acute infections • pain disorders: o migraine o rheumatic diseases o ulcerative colitis o fibromyalgia o Crohn´s disease o irritable bowel syndrome o others

Design outcomes

Primary

Measure	Time frame
The primary goal of the study is to get a better understanding of the influence of stress on pain in chronic and/or recurrent visceral pain. We aim to investigate whether acute stress can affect the perception and processing of acute pain on subjective, neural, endocrine and physiological levels and systematically compare the underlying mechanism in patients and healthy controls. Planned: N=60 patients and N=60 matched healthy controls	—

Measure

Time frame

The primary goal of the study is to get a better understanding of the influence of stress on pain in chronic and/or recurrent visceral pain. We aim to investigate whether acute stress can affect the perception and processing of acute pain on subjective, neural, endocrine and physiological levels and systematically compare the underlying mechanism in patients and healthy controls. Planned: N=60 patients and N=60 matched healthy controls

—

Secondary

Measure	Time frame
Questionnaire and demographic data, such as age, will be analyzed as covariates.	—

Countries

Germany

Contacts

Public ContactKatharina van Stein

Institut für medizinische Psychologie, Uniklinikum Heidelberg

Katharina.vanStein@med.uni-heidelberg.de06221 56-8138

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026