COVID-19
Conditions
Interventions
Group 1: Single application of hydrogen peroxide (H2o2) 1% (10ml for 30s)
Group 2: Single application of a total of 15 ml of chlorhexidine (CHX 0.05%) and cetylpiridinium chloride (CPC 0.05%) for 30 s
Sponsors
Universität Witten/Herdecke Fakultät für Gesundheit (Department für Zahn-, Mund- und Kieferheilkunde)Lehrstuhl für Zahnerhaltung und Präventive Zahnmedizin
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: - Age: 18-80 years - Positive, confirmed disease with Covid-19 - Good general condition of the patient - No elevated temperature - No elevated blood pressure/pulse - No increased respiratory rate - No medication intake - Presentation of the consent form of the Subject
Exclusion criteria
Exclusion criteria: - severe general illness - Subjects with physical and/or mental disabilities mental disabilities with limited manual and cognitive abilities and therefore no comparability possible - Allergic reactions to the substances used in the study (e.g. hydrogen peroxide) - alcohol abuse - Lack of compliance, so that it cannot be ensured that the patients* comply with the study protocol. - Pregnancy and lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The aim of this study is to determine the virus detection in the throat, using polymerase chain reaction (PCR), in SARS-CoV-2 patients after using the four different mouthwashes with different concentrations and residence time in the mouth. | — |
Secondary
| Measure | Time frame |
|---|---|
| The second goal is to find out a correlation of the viral load, between the saliva-NaCl mixture (rinsing with NaCl) and the throat swab. | — |
Countries
Germany
Contacts
Public ContactPeter Hahn
Universität Witten/Herdecke Fakultät für Gesundheit (Department für Zahn-, Mund- und Kieferheilkunde)Lehrstuhl für Zahnerhaltung und Präventive Zahnmedizin
Outcome results
None listed