TEMPERATURE-DEPENDENT EROSIVITY OF DRINKS - AN IN-SITU STUDY

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00023724

Enrollment

Registered

2021-01-11

Start date

2021-01-19

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K03.2

Interventions

Group 1: Randomized allocation of sterilized bovine enamel specimens (n = 2 each) worn in dental splints for the sip-wise intake of following beverages in a randomized order. Arm 1: 100 ml Orange Juic

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Systemically healthy adults aged = 18 years - Physiological saliva flow rates (stimulated: >1 ml/min, unstimulated: >0.25 ml/min) - Good oral health (no obvious cavities or significant gingivitis/periodontitis)

Exclusion criteria

Exclusion criteria: - General/systemic illness - Known allergy against any of the applied beverages

Design outcomes

Primary

Measure	Time frame
Sip-wise intake (drinking) of following widely available beverages (the sequence of the intake of beverages will be randomized): 1) 100 ml Orange Juice at 5 °C within 1 minute 2) 100 ml Orange Juice at 21 °C within 1 minute 3) 100 ml Coca Cola Zero at 5 °C within 1 minute 4) 100 ml Coca Cola Zero at 21 °C within 1 minute 5) 100 ml Sprite Zero at 5 °C within 1 minute 6) 100 ml Sprite Zero at 21 °C within 1 minute 7) 150 ml Twinings Fruit tea at 21 °C within 2 minutes 8) 150 ml Twinings Fruit tea at 55 °C within 2 minutes. Thereafter assessment of erosive enamel softening as determined by surface microhardness measurements of the enamel specimens.	—

Measure

Time frame

Sip-wise intake (drinking) of following widely available beverages (the sequence of the intake of beverages will be randomized): 1) 100 ml Orange Juice at 5 °C within 1 minute 2) 100 ml Orange Juice at 21 °C within 1 minute 3) 100 ml Coca Cola Zero at 5 °C within 1 minute 4) 100 ml Coca Cola Zero at 21 °C within 1 minute 5) 100 ml Sprite Zero at 5 °C within 1 minute 6) 100 ml Sprite Zero at 21 °C within 1 minute 7) 150 ml Twinings Fruit tea at 21 °C within 2 minutes 8) 150 ml Twinings Fruit tea at 55 °C within 2 minutes. Thereafter assessment of erosive enamel softening as determined by surface microhardness measurements of the enamel specimens.

—

Secondary

Measure	Time frame
Determination of the temperature-dependent erosivity of drinks with erosive enamel softening serving as a proxy.	—

Countries

Switzerland

Contacts

Public ContactValerie Steiger-Ronay

University of ZurichCenter for Dental Medicine (ZZM)Clinic of Preventive Dentistry, Periodontology and Cariology

valerie.steiger@zzm.uzh.ch+41 44 634 39 36

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026