Pilot study: clinical and physiological effects of a high-intensity interval training (HIIT) in patients with post-traumatic stress disorder

Pilot study: clinical and physiological effects of a high-intensity interval training (HIIT) in patients with post-traumatic stress disorder - HIIT-PTSD

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00023643

Enrollment

Registered

2021-03-02

Start date

2021-03-02

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F43.1

Interventions

Group 1: 12-day High-intensity interval training (6x20 minutes, every other day) Group 2: 12-day Training of low intensity (6x20 minutes, every other day)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Minimum age of 18 years 2. Diagnosis of PTSD according to DSM-5 3. Sufficient knowledge of german to communicate with the examiner and to fill in the Questionnaires 4. Ability to regularly participate in therapy 5. signed written consent to participate in the study

Exclusion criteria

Exclusion criteria: 1. Diagnosis of the following other psychiatric illnesses: lifetime diagnosis of schizophrenia or bipolar I disorder, acute alcohol or substance dependence without abstinence for at least 2 months. 2. Acute suicidality (suicide attempt in the last 2 months, currently urgent suicide ideations/impulses) 3. contraindications to participation in endurance training 4. Trauma-focused psychotherapy at the time of the study 5. Psychotherapeutic treatment for less than two months 6. Change in psychopharmacotherapy within the last two months before or at the time of the study 7. Practicing endurance exercises for more than 75 minutes / week or yoga for more than 75 minutes / week within the last two months

Design outcomes

Primary

Measure	Time frame
Symptom severity of post-traumatic stress disorder at post [1 week after the last day of the intervention] and follow-up [6 weeks after the last day of the intervention]	—

Secondary

Measure	Time frame
- Dissociative symptoms at post [1 week after the last day of the intervention] and follow-up [6 weeks after the last day of the intervention] - Depressive symptoms at post [1 week after the last day of the intervention] and follow-up [6 weeks after the last day of the intervention] - General psychopathology at post [1 week after the last day of the intervention] and follow-up [6 weeks after the last day of the intervention] - Heart rate variability at post [1 week after the last day of the intervention] and follow-up [6 weeks after the last day of the intervention] - adiponectin and the neurotrophin BDNF at the last day of the intervention	—

Measure

Time frame

- Dissociative symptoms at post [1 week after the last day of the intervention] and follow-up [6 weeks after the last day of the intervention] - Depressive symptoms at post [1 week after the last day of the intervention] and follow-up [6 weeks after the last day of the intervention] - General psychopathology at post [1 week after the last day of the intervention] and follow-up [6 weeks after the last day of the intervention] - Heart rate variability at post [1 week after the last day of the intervention] and follow-up [6 weeks after the last day of the intervention] - adiponectin and the neurotrophin BDNF at the last day of the intervention

—

Countries

Germany

Contacts

Public ContactKathlen Priebe

Psychiatrische Universitätsklinik der Charité im St. Hedwig-Krankenhaus

kathlen.priebe@charite.de+49 30 2311 1880

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026