L40
Conditions
Interventions
Group 1: Neuroinflammatory parameters (IL-6
IL-17 and Substance P) will be determined at one time point in patients with psoriasis and healthy skin controls. These parameters will be determined in suction-blister-fluid, which will be gathered t
Sponsors
Universitätsklinikum Gießen und Marburg
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: clinically diagnosed psoriasis for at least 6 months, high or low social anxiety (determined by means of the SOZAS ("Soziale Angstskalen")), sufficient German language skills in order to understand and fill in the questionnaires
Exclusion criteria
Exclusion criteria: other itch-related (skin-)disease, severe psychological disorder
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Social Anxiety; Itch intensity; IL-6; IL-17; Substance P Neuroinflammatory parameters will be determined in the suction-blister-fluid, which will be gathered using the suction-blister-methods. Using this method suction-blisters will be induced on the skin by a vacuum. Socialy anxiety will be determined by means of validated questionnaires, namely the social interaction anxiety scale and the social phobia scale. Itch intensity, namely the average and maximal itch intensity during the last 24 hours, will be measured by visual analog scales (0-10). | — |
Countries
Germany
Contacts
Public ContactChristina Schut
Institut für Med. PsychologieJustus-Liebig-Universität Gießen
Outcome results
None listed