healthy volunteers
Conditions
Interventions
Group 1: Volunteers are exposed to a high-melanopic light source (i.e., with a spectral peak at 465nm) from 1h50min to 50min prior to habitual bed time for a total duration of 1 hour. Photopic lux are
Sponsors
Universität Basel
Eligibility
Sex/Gender
All
Age
18 Years to 30 Years
Inclusion criteria
Inclusion criteria: • Age: 18-30 years • Body Mass Index: 18.5-24.9 (i.e. normal weight according to WHO criteria) • Informed consent as documented by signature of the participant
Exclusion criteria
Exclusion criteria: • Previous enrolment in the study’s project part • Investigator’s family members, employees or other dependent persons • Left-handedness • Pregnancy • Hearing difficulties/ a hearing aid • Chronic or debilitating medical conditions • Drug use • Shift work 2 time zones) 7) • Short and long sleep duration (subjective sleep duration on workdays outside 6-10h according to the MCTQ) Exclusion criteria due to study requirements • Inability to understand and/or follow procedures • Mother tongue other than the project language (German) • Non-adherence to sleep/wake times during the ambulatory part
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcomes are EEG-derived parameters of event-related oscillatory activity (event-related de-/synchronisation in the 1-15 Hz range) as well as event-related potentials (mismatch negativity, P3, K-complex-like responses). The outcomes are assessed using an acoustic stimulation paradigm (i.e., an oddball task) participants undergo during the light exposure in the evening as well as during the whole night. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are sleep quality indexes, salivary melatonin levels as well as the spectral composition of the EEG signal during resting-state recordings (wakefulness) and stimulation-free periods during sleep. Moreover, also subjective sleepiness (assessed by a questionnaire) is a secondary outcome. | — |
Countries
Switzerland
Contacts
Public ContactChristine Blume
Universität Basel
Outcome results
None listed