I26
Conditions
Interventions
Group 1: Healthy subjects (n = 20): ASL-MRI of the lungs is performed twice (7 days apart) in order to determine the retest reliability.
Group 2: Patients (n = 127): The study-related ASL-MRI examinat
Sponsors
Universitätsklinikum Tübingen
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: • Clinical suspicion of pulmonary artery embolism, • Performing a CT-pulmonary angiography based on a clinical indication within the last 72 hours, • Stable patient due to the medical assessment of the referring doctor, • Age =18 years, • Written consent from the patient.
Exclusion criteria
Exclusion criteria: • Presence of non-MR-compatible implants or any kind of metal in and on the body (e.g. pacemakers, artificial heart valves, metal prostheses, implanted, magnetic metal parts, coils, etc. that are not MR-compatible), • People who report a hearing impairment or an increased sensitivity to loud noises, • People with reduced temperature sensation and / or increased sensitivity to warming of the body, • People who suffer from claustrophobia, • Limited ability of the patient or test person to give consent, • Obesity with a body weight of> 150 kg.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic accuracy of ASL-MRI with regard to detection / exclusion (positive or negative) of pulmonary artery embolism (sensitivity and specificity). | — |
Secondary
| Measure | Time frame |
|---|---|
| • Creation of a qualitative assessment score of the image quality for the ASL-MRI, • Comparison of the examination time of both procedures, ASL-MRT and CT-pulmonary angiography (each time start-end examination), • Development of an ASL-MRI-based score for pulmonary artery embolism (quantitative lung perfusion index). | — |
Countries
Germany
Contacts
Public ContactFerdinand Seith
Radiologische Universitätsklinik Tübingen Diagnostische & Interventionelle Radiologie
Outcome results
None listed