G20.0 G20.1
Conditions
Interventions
Group 1: For all participants, motor scores (UPDRS, Hoehn & Yahr) and the Non-motor-Symptom Scale will be assessed.
Postganglionry sudomotor sympathetic efferences are measured with QSART (Quantitat
Sponsors
Klinik für Neurologie und Neurophysiologie Universitätsklinikum Freiburg
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Gender: Both, male and female Minimum age: 18 years Maximum age: no maximum age Further inclusion criteria - Outpatient or inpatient presentation in the clinic for neurology - Diagnosis M. Parkinson according to the currently valid international diagnostic criteria
Exclusion criteria
Exclusion criteria: -Failure to provide oral and written informed consent to the patient or the patient's caregiver - MME 16 - Drugs that can influence the measurements, such as anticholinergics - Polyneuropathy (pathological NLG, pallaesthesia or ASR) or diseases that can be associated with polyneuropathy, such as diabetes mellitus.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of the lesions to autonomous and somatosensory nerve fibers (comparison with normative values for the respective investigation) and correlation between the lesions. | — |
Secondary
| Measure | Time frame |
|---|---|
| Do the autonomous and somatosensory assessments correlate with the disease stage and with other central or peripheral non-motor symptoms? For correlations: Spearman’s Rank correlation test, Wilcoxon-test. For categorical comparisons: Chi-Square-test. | — |
Countries
Germany
Contacts
Public ContactMichel Rijntjes
Klinik für Neurologie Universitätsklinikum Freiburg
Outcome results
None listed