Influence of "blood flow restriction training" (BFR) on systematic intravasal blood pressure, regulation of multiple growth factors, products of cell death, influence on arterial and venosus blood pressure and anabolic hormone and apoptosis

Influence of "blood flow restriction training" (BFR) on systematic intravasal blood pressure, regulation of multiple growth factors, products of cell death, influence on arterial and venosus blood pressure and anabolic hormone and apoptosis - Invasive analysis of blood-flow-restriction training (LI vs. LI-BFR vs. HI)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00023481

Enrollment

Registered

2020-11-04

Start date

2021-01-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary reasearch with healthy individuals

Interventions

Group 1: Low intensity strenght training (LI) Following LI with 30% of maximal strength of resistance. There will be four sets of repetition until fatigue, split by one minute breaks. Group 2: Low int

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: no pre existing condition, no contra indication, no pathalogy of (training) upper limb, written consent of patient

Exclusion criteria

Exclusion criteria: contra intication, hypertonia, open wound or fracture of upper limb, systemic inflamation, absence of written consent of patient

Design outcomes

Primary

Measure	Time frame
The examination of following researche hypothesis: H1: regardless of using low resistance LI-BFR results in stronger metabolic difference with electrolythe differal when compared to LI and HI during physical load until muscular fatigue. H2: the difference of local venosus electrolythe differal ([Na+], [Ca2+], [K+]) correlate with metabolism ([La-], [HCO3-]) and neuromuscular activation of used muscles. H3: The difference of non-invasive muscular testing (neuromuscular activation, contraction speed, dilatation of muscle following TMG, maximal strenght) correlate with local and systemic electrolythe differal and can be seen as forecast parameter. H4: stratification of risc 1. of BFR-training: LI-BFR results in higher differal of venosus [K+] during and after the session compared to different training H5: stratification of risc 2. of BFR-training: LI-BFR resulty in acute pathological reflux compared to different training	—

Measure

Time frame

The examination of following researche hypothesis: H1: regardless of using low resistance LI-BFR results in stronger metabolic difference with electrolythe differal when compared to LI and HI during physical load until muscular fatigue. H2: the difference of local venosus electrolythe differal ([Na+], [Ca2+], [K+]) correlate with metabolism ([La-], [HCO3-]) and neuromuscular activation of used muscles. H3: The difference of non-invasive muscular testing (neuromuscular activation, contraction speed, dilatation of muscle following TMG, maximal strenght) correlate with local and systemic electrolythe differal and can be seen as forecast parameter. H4: stratification of risc 1. of BFR-training: LI-BFR results in higher differal of venosus [K+] during and after the session compared to different training H5: stratification of risc 2. of BFR-training: LI-BFR resulty in acute pathological reflux compared to different training

—

Secondary

Measure	Time frame
patient satisfaction and assessment of practicability for security following BFR, LI- or HI-training	—

Countries

Germany

Contacts

Public ContactAlexander Franz

Uniklinik Düsseldorf

alexander.franz@hhu.de+49 (0) 2 11-81 00

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026