G30.9 F06.7
Conditions
Interventions
Group 1: The plasma samples already available from the registrants of the Center for Memory Disorders (ZfG) at Cologne University Hospital will be shipped to Sweden and examined there by the laborator
Sponsors
Direktor der Klinik für Psychiatrie und Psychotherapie Universitätsklinikum Köln (AöR)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: We include patients who have registered with memory disorders at the Center for Memory Disorders (ZfG) of the Clinic for Psychiatry and Psychotherapy at the University Hospital of Cologne and who have given written consent to give a blood sample for research purposes.
Exclusion criteria
Exclusion criteria: Patients who refuse to have their blood drawn for research purposes are excluded. Further exclusion criteria are not defined.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The aim of this work is the analysis of research blood samples of the Center for Memory Disorders for the determination of plasma Aß40, Aß42, Aß42/Aß40, Aß42xTau, t-Tau, p-tau181 and NFL and the comparison between SCD, MCI and DAT to investigate whether the biomarkers in plasma are suitable for the diagnosis of the different diagnostic groups. For this purpose, the protein concentrations of the plasma samples are determined using SIMOA-HD analyzers. | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of plasma biomarkers with different diagnostic tools, such as neuropsychological testing and cerebrospinal fluid (CSF) diagnostics. For this purpose, statistical comparison using linear regression and ROC analyses will be sought. | — |
Countries
Germany
Contacts
Public ContactAnn-Katrin Schild
Klinik für Psychiatrie und Psychotherapie der Uniklinik Köln
Outcome results
None listed