G20
Conditions
Interventions
Group 1: Clinical visit, that are performed, because automatic evaluation of app-data suggests relevant clinical deterioration
Group 2: clinical visits, that are randomly triggered without suspicion o
Sponsors
Charité Campus Charité Mitte
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - definite diagosis of parkinsons disease - privately owned smartphone (Android or iOS operating system) and basic knowledge in using apps - able to understand study conditions and questiones asked in patient questionnaires
Exclusion criteria
Exclusion criteria: - cognitive deficites, that obviate fulfilling the inclusion criteria - comorbidities, whose influence on quality of life exceeds the influence of parkinsons disease considerably as rated by the study physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Correlation coefficient with confidence interval between self-rated mobility on visual analogue scale within 2 weeks before study visit and MDS-UPDRS-III at the day of visit. Observation for 6 to 24 months per patient. Analysis: random intercept model | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Correlation between self-rated general condition and QoL in PDQ-39-score as well as between step count and self-rated mobility (similar analysis to primary endpoint). 2) Sensitivity, specificity and predicitve values between gold standard (relevant deterioration/no relevant deterioration as determined in clinials visit) and independent variable (estimation from smartphone data). 3) Association between severity of clinical deterioration estimated in clinical visit or in smartphone app. 4) Changes in self-rating after therapeutic interventions. | — |
Countries
Germany
Contacts
Public ContactAndrea Kühn
Klinik für Neurologie Charite - Universitätsmedizin Berlin
Outcome results
None listed