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Patency of aortocoronary vein grafts in aortic vascular prostheses compared to native aorta

Patency of aortocoronary vein grafts in aortic vascular prostheses compared to native aorta - PAVAPRO

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00023388
Enrollment
210
Registered
2020-11-12
Start date
2021-04-27
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Venous coronary artery bypass grafting with proximal anastomosis in an ascending aorta prosthesis

Interventions

Group 1: Patients of the University of Ulm Medical Center who received a venous aortocoronary bypass graft with the proximal anastomosis in an ascending aortic prosthesis. These patients will be recru

Sponsors

Universitätsklinikum Ulm, Klinik für Herz-, Thorax- und Gefäßchirurgie
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Treatment group: patients who received at least one vein graft with the proximal anastomosis in an aortic prosthesis between 2011 and 2018. Control group: patients who received at least one vein graft with the proximal anastomosis in the native aorta between 2011 and 2018

Exclusion criteria

Exclusion criteria: Intolerance towards the CT contrast agent Imeron 400 or any of the other medications used during imaging (metoprolol, organic nitrates); renal insufficiency affecting contrast agent elimination; hyperthyroidism; bradyarrhythmia; unwillingness to participate; inability to provide informed consent; laboratory parameters prior to imaging which suggest an elevated risk; control group: only symptomatic patients

Design outcomes

Primary

MeasureTime frame
Number of obstructed vein grafts at the time of analysis, scheduled for 2021. The observation period depends on the date of operation and is from 3 to 10 years.

Secondary

MeasureTime frame
The analysis is scheduled for 2021. The observation period depends on the date of operation and is from 3 to 10 years. (1) Assessment of CT scan: number of patients with at least one obstructed venous bypass graft; fraction of obstructed vein grafts per patient. (2) Assessment of patient files: cardiovascular death; rehospitalization; reinfarction

Countries

Germany

Contacts

Public ContactChristian Skrabal

Universitätsklinikum Ulm, Klinik für Herz-, Thorax- und Gefäßchirurgie

christian.skrabal@uniklinik-ulm.de0731-500-54303

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026