Allergic rhinitis Asthma Chronic rhinosinusitis J30 J45 J32
Conditions
Interventions
Group 1: Informed Consent Procedure
Pregnancy test in urine for female patients with childbearing potential
Clinical Examination of the respiratory tract
Collection of serum and plasma, nasal secretio
Sponsors
Klinikum rechts der Isar der Technischen Universität München
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Individuals in good health otherwise from respiratory disease 2. Patients suffering from at least two symptoms that suggest Respiratory Inflammatory Disease: - Recurrent Sneeze - Itchy Eyes - Anterior or posterior rhinorrhea - Blocked Nose - Cough - Wheeze or Asthma attacks - Seasonal variation of airway symptoms 3. Age between 18 and 75 years
Exclusion criteria
Exclusion criteria: 1. Inability to understand or to communicate with investigator or to understand the aim of the study 2. Any currently relevant medical history of addiction to alcohol, drugs or medical substances 3. Any currently relevant medical history of clinically significant internal disease that is not primarily affecting the airways and that is not controlled by medication 4. Concommitant medication: Intake of topical nasal steroids, systemic leukotriene antagonists or any antihistamines within the last 7 days before study visit or systemic glucocorticoids within the last 10 days or Specific Immunotherapy within the last 5 years 5. Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess sensitivity and specificity of biomarkers in local airway secretions in comparison to serum expression. | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess tolerability of sampling methods. | — |
Countries
Germany, Poland
Contacts
Public ContactClaudia Jerin
Klinikum rechts der Isar der Technischen Universität München
Outcome results
None listed