G20.11
Conditions
Interventions
Group 1: Patients with idiopathic Parkinson's syndrome are examined at rest on one appointment under their usual dopaminergic medication using electroencephalography (EEG). This means that the test su
Sponsors
Uniklinik Leipzig Klinik für Neurologie
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: Female and male participants between 30 and 80 years of age; normal vision (also corrected, e.g. by glasses/contact lenses) according to self-disclosure, signing of consent form; specific for MRI: participation in a detailed explanation of possible contraindications and risks during an MRI examination at 3 Tesla, signing of consent forms, specific for Parkinson's patients: Confirmed diagnosis of an idiopathic Parkinson's syndrome with mild to severe bradykinesis and/or rigor as predominant symptomatology (Hoehn & Yahr 1 - 4)
Exclusion criteria
Exclusion criteria: Non-consent or inability of the subject to consent to participate in the study; Alcohol or drug abuse; Other neurological diseases with the exception of idiopathic Parkinson's syndrome, psychiatric diseases; Complex and extensive medication which, in the opinion of the investigator, influences the performance of the experiments; Claustrophobia; Pregnancy according to self-disclosure; Specific for MRI: Contraindication for MRI examination; Specific for Parkinson's patients: pronounced rest tremor
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in oscillatory activity in the "on" and "off" state of dopaminergic medication in patients with idiopathic Parkinson's syndrome and in comparison to healthy controls | — |
Secondary
| Measure | Time frame |
|---|---|
| no secondary outcome | — |
Countries
Germany
Contacts
Public ContactChristoph Mühlberg
Neurologie Uniklinik Leipzig
Outcome results
None listed