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Feasibilitystudy of leprosy active case findings by contact tracing and the administration of a single dose of rifampicin as post-exposure prophylaxis in Senegal

Feasibilitystudy of leprosy active case findings by contact tracing and the administration of a single dose of rifampicin as post-exposure prophylaxis in Senegal - LPEP-Senegal

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00023299
Enrollment
14000
Registered
2020-10-20
Start date
2020-10-20
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

A30

Interventions

Group 1: Active case finding for new leprosy cases in the vicinity of reported cases in the last 5 years and post-exposure prophylaxis (PEP) with a single dose of rifampicin 10 mg / kg, max 600 mg for

Sponsors

Deutsche Lepra und Tuberkulosehilfe e.V.
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to No maximum

Inclusion criteria

Inclusion criteria: Anyone usually residing in the villages reporting leprosy cases in the last five years and are considered for active screening and aged 2 years or over regardless of their sex, social, ethnic or religious affiliation.

Exclusion criteria

Exclusion criteria: - Refusal to give informed consent for screening or for the disclosure of the diagnosis to other members of his family - Refusal to give informed consent for PEP - Age <2 years - New leprosy confirmed (cases should be put on MDT if they have not yet received MDT) or suspected, until the disease is ruled out - overt signs and / or symptoms of tuberculosis (patients with any of the following symptoms should be referred to a tuberculosis diagnostic center for screening for the following symptoms: cough for more than two weeks, night sweats, unexplained fever , weightloss) - Treatment with rifampicin for a given reason within the last two years (e.g. for treatment of tuberculosis or leprosy, or as contact with another index case) - Pregnancy (PEP can be given after childbirth) - History of liver problems (eg jaundice) or kidney problems - Allergy to rifampicin

Design outcomes

Primary

MeasureTime frame
newly diagnosed patients during active case finding activity and in the following two years

Secondary

MeasureTime frame
Grade 2 disabilities

Countries

Senegal

Contacts

Public ContactMadoky Magatte Diop

spécialiste en Médecine Interne et en Léprologie, chef du service de Médecine Interne de l’Hôpital Régional de Thiès

maxmadoky@hotmail.com+221776362822

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026