R20.8 R21
Conditions
Interventions
Group 1: 5-10 healthy human volunteers are subjected to the topical application of samples in order to further evaluate the skin irritation induced by the use of each product. The samples are applied
the assessment of skin irritation is conducted 20 minutes later on each area. The tests are carried out with a MultiProbe Adapter System from Courage&Khazaka Electronics (Koln, Germany), equipped with
Sponsors
Victor Babes University of Medicine and Pharmacy
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Human volunteers without skin lesions.
Exclusion criteria
Exclusion criteria: 1. Subjects with systemic disorders, atopic dermatitis, eczema, psoriasis 2. Subjects with a condition or receiving a medication and/or with a history of medical/surgical events which, in the opinion of the Investigator, could compromise the safety of the subject or affect the outcome of the study 3. Subjects with a history of skin cancer
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A MultiProbe Adapter System from Courage&Khazaka Electronics (Koln, Germany), equipped with a Tewameter® TM300 probe and a Mexameter® MX18 probe will be used to measure the changes of transepidermal water loss and erythema for 15 days (sample applications and skin evaluations every third day). | — |
Secondary
| Measure | Time frame |
|---|---|
| The evaluations period is 15 days. Data will be analysed using single-ANOVA and compared with the references from scientific literature. | — |
Countries
Romania
Contacts
Public ContactZoltan Dudas
Neutron Spectroscopy Department, Centre for Energy Research
Outcome results
None listed