Skip to content

Influence of single-sided deafness and cochlear implant on the central auditory pathway

Influence of single-sided deafness and cochlear implant on the central auditory pathway

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00023227
Enrollment
30
Registered
2021-05-04
Start date
2023-01-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

H90.4

Interventions

Group 1: Normal-hearing subjects Hearing test to measure speech recognition in background noise. Positron emission tomography (PET) with acoustic, visual and sensorimotor stimulation Group 2: Single-s

Sponsors

HNO-Uniklinik Freiburg
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: SSD CI recipients 1. diagnosed with SSD according to the definition of Vincent et al. (2015): hearing of the poorer ear: profound sensorineural hearing loss bordering on deafness; hearing of the better ear: air conduction hearing threshold in the range up to and including 4 kHz = 30 dB HL. 2. fitted with a CI on the right. 3. = 6 months of hearing experience with CI. NH subjects 1. hearing in both ears: Air conduction hearing threshold in the range 125-8000 Hz = 20 dB HL.

Exclusion criteria

Exclusion criteria: All groups 1. age 65 years 2. left-handed 3. relevant neurological or psychiatric disease 4. medical conditions that would indicate inadequate compliance with PET 5. pregnancy, breast feeding, current desire to have children 6. past study-associated radiation exposure 7. occupational exposure to radiation 8. participants who refuse the report of incidental findings.

Design outcomes

Primary

MeasureTime frame
Which cortical areas show neuronal activity during auditory, visual, and somatosensory stimulation in [15O]water PET examination?

Secondary

MeasureTime frame
Collection of significant differences between the SSD CI subjects and the NH subjects.

Countries

Germany

Contacts

Public ContactIva Speck

HNO-Uniklinik Freiburg

iva.speck@uniklinik-freiburg.de0761/270-41964

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026