Investigation of Red and White Blood Cell Deformability in Sepsis Patients using RT-DC Technique

Investigation of Red and White Blood Cell Deformability in Sepsis Patients using RT-DC Technique - RT-DC_Sepsis

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00023225

Enrollment

Registered

2020-11-02

Start date

2023-10-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

A40 A41 R65

Interventions

Group 1: Sampling: 6 blood probes from 3 successive days starting with date of suspected sepsis. Measures: RT-DC, CRP, PCT, IL-6

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Intensive care patient with suspected sepsis

Exclusion criteria

Exclusion criteria: none

Design outcomes

Primary

Measure	Time frame
Analysis of the RT-DC parameters / cell deformation, especially of the leukocytes in the clinical course (analysis of the kinetics), which are characterized by changes in cell size, deformation and brightness, in relation to the actual sepsis onset.	—

Secondary

Measure	Time frame
RT-DC measurements at different times to analyze the same blood sample 1h, 2h, 4h, 8h after blood sampling to clarify the questions: How quickly does the fresh blood have to be analyzed? How stable are the measurements? Comparison of the RT-DC parameters with proven infection parameters CRP, PCT, IL-6 (correlation analysis, analysis of the significance of the new parameters)	—

Countries

Germany

Contacts

Public ContactMatthias Gründling

Qualitätsmanagementprojekt Sepsisdialog, Universitätsmedizin Greifswald, Klinik und Poliklinik für Anästhesiologie und Intensivmedizin

Matthias.Gruendling@med.uni-greifswald.de00493834865862

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026