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Register for People Experiencing Psychosis Berlin: A systematic multilevel comparison of physiological and psychopathological characteristics of exogenous and endogenous psychoses

Register for People Experiencing Psychosis Berlin: A systematic multilevel comparison of physiological and psychopathological characteristics of exogenous and endogenous psychoses - REPOSE

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00023222
Enrollment
300
Registered
2020-12-04
Start date
2020-04-15
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F23 F20-F29 F05.9 F10-F19 F00-F09 T44

Interventions

Group 1: Persons with a so-called acute psychotic syndrome are to be included (i.e. characteristic changes in behaviour and perception with formal and substantive thought disorders, hallucinations) e.

Sponsors

Klinik für Psychiatrie und Psychotherapie der Charité - Universitätsmedizin Berlin
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: Prerequisite for inclusion in the register study is the ability to consent - Written consent to participation - Persons with a so-called acute psychotic syndrome should be included (i.e. characteristic changes in behavior and perception with formal and content-related thought disorders, hallucinations), e.g. in connection with - neurodegenerative diseases - Autoimmune encephalopathies - drug or intoxication-related delirium - metabolic delirium - Alcohol Withdrawal delirium - postoperative delirium - acute polymorphic schizophreniform disorder - schizophrenia - schizoaffective disorder

Exclusion criteria

Exclusion criteria: - Withdrawal of consent to participate in the study - Severe diseases with a poor prognosis or complex constellations of diseases with numerous comorbidities [e.g. terminal renal failure, liver failure, therapy-resistant diabetes mellitus or epilepsy, permanent severe impairment of cognitive function, Mini-Mental Status Test (MMST) <13].

Design outcomes

Primary

MeasureTime frame
The primary objective of the planned registry study is to use machine learning methods [in particular sparse canonical correlation analysis (sCCA) as well as convolutional neural networks (CNN) and Bayesian networks (BN)] to identify correlations between psychopathological symptoms on the one hand and imaging and physiological parameters (Ethiopathogenesis) on the other hand.

Secondary

MeasureTime frame
Based on the identified statistical relations, corresponding parameters will be evaluated with regard to their predictive value for the clinical course of psychotic symptoms. In addition, the register study will allow the calculation of epidemiological parameters and their relation to the course of disease and therapy.

Countries

Germany

Contacts

Public ContactSurjo Soekadar

AG Klinische Neurotechnologie der Klinik für Psychiatrie und Psychotherapie, Charité - Universitätsmedizin Berlin

surjo.soekadar@charite.de+49-30-450 528153

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026