What is the effect of PEEP setting on the distance between the subclavian vein and pleura and on the cross-sectional area of the subclavian vein?

What is the effect of PEEP setting on the distance between the subclavian vein and pleura and on the cross-sectional area of the subclavian vein? - SUBCLAVIA-Study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00023173

Enrollment

Registered

2022-03-01

Start date

2020-02-28

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anatomic positional changes of certain vessels during mechanical ventilation

Interventions

Group 1: Observation study, no control group This study will sonographically determine the distance between the subclavian vein and the parietal pleura at different PEEP levels. In addition, the infl

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: mechanical ventilation

Exclusion criteria

Exclusion criteria: Intravascular catheters and/or probes in either subclavian vein, ventilation parameters: PEEP >15

Design outcomes

Primary

Measure	Time frame
Distance between subclavian vein and pleura at different PEEP levels, the distance is measured by ultrasound 2 minutes after changing the ventilatory setting.	—

Secondary

Measure	Time frame
Change in the vessel diameter of the subclavian vein.	—

Countries

Germany

Contacts

Public ContactChristine Eimer

UKSH Campus Kiel

christine.eimer@uksh.de043150020801

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026