F20
Conditions
Interventions
Group 1: Measurement of AChE- and BChE-activity in 50 patients with schizophrenia. First measurement upon admission to the psychiatric ward (admission ward). Further 3 measurements over 3 consecutive
Sponsors
Klinik für Psychiatrie und Psychotherapie III Universitätsklinikum Ulm
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Age > 18 years DSM-classified schizophrenic disease (pre-existing or initial diagnosis) verbal and written consent of the patients before starting the measurements
Exclusion criteria
Exclusion criteria: Age < 18 years Cognitive impairment that makes participation in the study impossible Severe visual and hearing impairments patients who are not able to give informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AChE-activity in patients with schizophrenia compared to the healthy collective BChE-activity in patients with schizophrenia compared to the healthy collective | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation of BNNS (Brief Negative Symptom Scale) with AChE-, BChE-activity Correlation of SNS (self-evaluation of negative symptoms) with AChE-, BChE-activity Correlation between the course of AChE-, BChE- activity and the need for antipsychotics (total dose, dose per 24 hours) Correlation between disease duration, based on initial diagnosis and AChE-, BChE-activity. | — |
Countries
Germany
Contacts
Public ContactCarlos Schönfeldt-Lecuona
Klinik für Psychiatrie und Psychotherapie III Universitätsklinikum Ulm
Outcome results
None listed